I would have a post TNG original timeline show with Worf as captain, with Geordie, Seven, Chakotay, Riker, Data, Quark and O'Brien as the crew who go off in a stolen Enterprise to the Gamma quadrant in search of glory (Worf), banging alien chicks (Riker and Chakotay), weird sexual preference acceptance (Geordie, Data and Seven obviously forming a threesome), treasure (Quark) and O'Brien just because he gets around.
Without the constraints of Star Fleet (they stole the ship) and Worf in charge, they get more and more f'd up along the way due to Worfs over-the-top assessments of everything (he says "prepare for ramming speed" every episode and is talked down...until one day he isn't). They start to solve most disputes by beaming people into space. Then into the same exact place as other people. Then, for a while, into their parents bedrooms while they're having sex. Then finally (at Data's suggestion) directly into coffins. Riker tries to take control of the ship as he's the ranking officer, but Worf wins out when it's discovered he got to 3rd base with Troi, but Riker only got to 2nd (Chakotay's is the deciding vote and this wins him over, but starts an ongoing sex-competition with him and Riker).
Quark appoints himself Chief Liaison Officer, and uses the position to constantly trick people with sexy holodeck scenarios (then blackmail them with the incriminating holo-tapes). In a funny yet tragic episode, they all try Ketrocel-White and become hopelessly addicted for the rest of the show. O'Brien is put in charge of the helm, but as he doesn't like it he eventually stops steering the ship and just let it push planets out of the way with the deflector shield. Riker and Chakotay's sex-competition gets way out of hand, but is dwarfed by Data and Seven having intense borg-nanobot sex while Geordie watches (and "calibrates").
Filled with frustration and self-loathing at narrowly losing the Christmas Bang-A-Thon to Chakotay, Riker agree's to let their away teams be made up of Rikers made from doing that double beaming thing (Will Riker really hated Tom Riker so he is secretly filled with sick satisfaction putting himself in redshirts and letting himself get killed). Worf's pony tail gets embarrassingly long. Quark starts selling the dead bodies of the Rikers to keep the ship afloat in the white stuff, but when it's not enough, Worf starts killing more and more people to fill the quotas. Geordie/Data/Seven build a baby, and it's literally the worst, so they give it to Q who shrinks it and puts it in Cisqo's ear so he thinks he's going mad. No-one ever time-travels, but sometimes Quark tricks them with the holodeck into thinking they have.
Worf makes everyone do batliff training even though they have phazers. O'Brien takes the training too far when he beats a friendly Cardassian to death and everyone is horrified, but O'Brien turns off the ship until everyone agree's it had to be done. Worf overdoses, which makes them all realise he has a serious meth problem (on top of the ketrocel-white addiction), and that they have been following a madman.
They all start taking meth, and the final series doesn't make any sense. It would be called "Star Trek: Worf Speed".
